World Neurosurgery
Volume 73, Issue 2 , Pages 108-111 , February 2010

Lipoglioblastoma: a lipidized glioma radiologically and histologically mimicking adipose tissue

  • Michael W. Johnson, MD, PhD

      Affiliations

    • Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    • ,
  • Doris Lin, MD

      Affiliations

    • Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    • ,
  • Bassam N. Smir, MD

      Affiliations

    • Greensboro Pathology Associates, PA Greensboro, NC 27415-3508, USA
    • ,
  • Peter C. Burger, MD

      Affiliations

    • Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    • Corresponding Author InformationCorresponding author. Department of Pathology, Baltimore, MD 21287, USA. Tel.: +1 410 955 8378; fax: +1 410 614 9310.

Received 30 June 2009 ,Accepted 16 July 2009.

References 

  1. Colnat-Coulbois S, Kremer S, Weinbreck N, et al. Lipomatous meningioma: report of 2 cases and review of the literature. Surg Neurol. 2008;69:398–402
  2. Elshihabi S, Husain M, Linskey M. Lipomatous medulloblastoma: a rare adult tumor variant with a uniquely favorable prognosis. Surg Neurol. 2003;60:566–570
  3. Fung KM, Fang W, Norton RE, et al. Cerebellar central liponeurocytoma. Ultrastruct Pathol. 2003;27:109–114
  4. Giangaspero F, Kaulich K, Cencacchi G, et al. Lipoastrocytoma: a rare low-grade astrocytoma variant of pediatric age. Acta Neuropathol. 2002;103:152–156
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  9. Kepes JJ, Rubinstein LJ. Malignant gliomas with heavily lipidized (foamy) tumor cells: a report of three cases with immunoperoxidase study. Cancer. 1981;47:2451–2459
  10. Kroh H, Matyja E, Marchel A, et al. Heavily lipidized, calcified giant cell glioblastoma in an 8-year-old patient, associated with neurofibromatosis type 1 (NF1): report of a case with long-term survival. Clin Neuropathol. 2004;23:286–291
  11. Matyja E, Naganska E, Zabek M, et al. Meningioma with the unique coexistence of secretory and lipomatous components: a case report with immunohistochemical and ultrastructural study. Clin Neuropathol. 2005;24:257–261
  12. Rickert CH, Riemenschneider MD, Schachenmayr W, et al. Glioblastoma with adipocyte-like tumor cell differentiation-histological and molecular features of a rare differentiation pattern. Brain Pathol. 2009;19:431–438
  13. Roncaroli F, Scheithauer BW, Laeng RH, et al. Lipomatous meningioma: a clinicopathologic study of 18 cases with special reference to the issue of metaplasia. Am J Surg Pathol. 2001;25:769–775
  14. Rosenblum MK, Erlandson RA, Budzilovich GN. The lipid-rich epithelioid glioblastoma. Am J Surg Pathol. 1991;15:925–934
  15. Ruchoux MM, Kepes JJ, Dhellemmes P, et al. Lipomatous differentiation in ependymomas: a report of three cases and comparison with similar changes reported in other central nervous system neoplasms of neuroectodermal origin. Am J Surg Pathol. 1993;22:338–346
  16. Sharma MC, Arora R, Lakhtakia R, et al. Ependymoma with extensive lipidization mimicking adipose tissue: a report of five cases. Pathol Oncol Res. 2000;6:136–140
  17. Vlodavsky E, Konstantinesku M, Soustiel JF. Gliosarcoma with liposarcomatous differentiation. The new member of the lipid-containing brain tumors family. Arch Pathol Lab Med. 2006;130:381–384
  18. Walter A, Dingemans KP, Weinstein HC, et al. Cerebellar astrocytoma with extensive lipidization mimicking adipose tissue. Acta Neuropathol. 1994;88:485–489

PII: S0090-3019(09)00655-7

doi: 10.1016/j.surneu.2009.07.036

World Neurosurgery
Volume 73, Issue 2 , Pages 108-111 , February 2010

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