NewsClearing Your Mind: A Glymphatic System?
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Other Possible Interactions
In 2013 Iliff and Nedergaard (4) summarized their present thoughts in an article in Stroke, noting that astrogliosis is a final common pathway of many mechanistically distinct forms of neurological injury such as trauma, hemorrhage, and ischemia. In their work, the AQP4 expression in injured brain is chaotic, in contrast to the normal state of AQP4 activity preponderance in the perivascular spaces, which may impede clearance of interstitial waste, not limited to beta amyloid or other aggregates
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Cited by (7)
Autoantibodies in central nervous system trauma: New frontiers for diagnosis and prognosis biomarkers
2020, Biomarkers for Traumatic Brain InjuryUpdate on cerebrospinal fluid research and cerebral drainage
2017, Osteopathische MedizinLymphatic drainage system of the brain: A novel target for intervention of neurological diseases
2018, Progress in NeurobiologyCitation Excerpt :The flow of CSF-ISF fluid through the brain parenchyma relies on astrocytic AQP4 water channels. In addition, cardiac, respiratory, and vasomotor pulsation patterns may contribute to the driving force of convective CSF fluid dynamics (Hui, 2015; Jiang et al., 2016). VRS, originally thought as a perivascular drainage pathway (Esiri and Gay, 1990; Zhang et al., 1990), are now considered to be the starting point of the glymphatic system.
Current understanding of central nervous system drainage systems: Implications in the context of neurodegenerative diseases
2020, Current Neuropharmacology