Case ReportCerebellar Peduncle Localized Oligodendroglioma: Case Report and Review of the Literature
Introduction
In 1926, Bailey and Cushing1, 2, 3 described oligodendroglioma as a tumor. Bailey and Bucy2, 3 were the first scientists who described clinical and histopathologic features of this tumor. Nearly 5% of all intracranial glial tumors consist of oligodendrogliomas.4, 5, 6 Oligodendrogliomas are dichotomized into grade II and grade III tumors according to the World Health Organization (WHO) classification of tumors affecting the central nervous system.7 Grade II tumors tend to have low mitotic activity and are uniform, but they might relapse. Some tumors are prone to anaplastic progression. Grade III oligodendrogliomas contain focal or diffuse anaplastic areas.4, 6
Many studies have been conducted to identify the clinical and morphologic features of oligodendrogliomas and to designate the factors affecting survival of patients since 1926.2
More than 90% of oligodendrogliomas are located supratentorially,1, 5 while posterior fossa tumors constitute <10% of all oligodendrogliomas.5, 8, 9, 10, 11 However, oligodendrogliomas arising in the cerebellar peduncle are significantly rare, even <1%.9, 12
Up to now, 6 oligodendroglioma cases localized in the cerebellar peduncle have been presented.12, 13, 14, 15 Solely, one of them originated from the cerebellar peduncle. In this case we aimed to discuss our second case originated from the cerebellar peduncle in company with the literature.
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Case Presentation
We report the case of a 43-year-old woman with known hypertension history. Her complaints were headache, perioral numbness, and gait abnormality.
The patient was operated for cerebellopontine angle tumor 2 years ago. Only the biopsy was conducted during this operation. The material was diagnosed as a low-grade glioma, and then the patient was referred to the Radiation Oncology Department.
The patient consulted our clinic because of her unrelieved complaints. Physical examination showed right
Discussion
Oligodendrogliomas are tumors that originate from one of the brain glial cells called an oligodendrocyte.4 Considering that oligodendrogliomas constitute 2%–5% of all primary brain tumors, this type can be counted as the third most common one.5, 11 Oligodendrogliomas constitute 4%–7% of primary intracranial gliomas in adults and 1% of primary central nervous system tumors in children.3, 4, 12
Infratentorial oligodendrogliomas constitute <10% of all oligodendroglial tumors.4, 5, 9, 11, 12
Acknowledgments
This article has been submitted as an e-poster presentation for the 16th World Congress of Neurosurgery that was held in August 2017 in Istanbul, Turkey. We would like to thank Professor Aydin Sav for pathologic examinations.
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Conflict of interest statement: The authors do not have any conflicts of interest to declare.
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Deceased in the writing process of the article.