Elsevier

World Neurosurgery

Volume 113, May 2018, Pages 62-66
World Neurosurgery

Case Report
Cerebellar Peduncle Localized Oligodendroglioma: Case Report and Review of the Literature

https://doi.org/10.1016/j.wneu.2018.02.008Get rights and content

Highlights

  • Oligodendrogliomas arising in the cerebellar peduncle are substantially rare, even <1%.

  • Up to now, 6 oligodendroglioma cases that are placed in cerebellar peduncle have been presented.

  • Our case will be the first pure cerebellar peduncle-originated case.

  • As a result, it should be kept in mind that oligodendrogliomas may be present as cerebellar peduncle localized tumors.

Background

Oligodendrogliomas constitute 5% of all primary brain tumors and are the third most common cancer among intracranial tumors. More than 90% of oligodendrogliomas have supratentorial localization. Oligodendrogliomas arising in cerebellar peduncle are substantially rare, <1%. Up to now, 6 oligodendroglioma cases with cerebellar peduncle localization have been presented. We aimed to discuss our World Health Organization grade II oligodendroglioma case, which originated from cerebellar peduncle in the light of literature.

Case Description

We report a case of 43-year-old woman. Her complaints were headache, perioral numbness and gait abnormality. Magnetic resonance imaging revealed cyst-like well-demarcated lesion localized in right cerebellar peduncle. Tumor excision was performed by turning around the tumor.

Conclusion

It should be kept in mind that oligodendrogliomas may be present as cerebellar peduncle localized tumors.

Introduction

In 1926, Bailey and Cushing1, 2, 3 described oligodendroglioma as a tumor. Bailey and Bucy2, 3 were the first scientists who described clinical and histopathologic features of this tumor. Nearly 5% of all intracranial glial tumors consist of oligodendrogliomas.4, 5, 6 Oligodendrogliomas are dichotomized into grade II and grade III tumors according to the World Health Organization (WHO) classification of tumors affecting the central nervous system.7 Grade II tumors tend to have low mitotic activity and are uniform, but they might relapse. Some tumors are prone to anaplastic progression. Grade III oligodendrogliomas contain focal or diffuse anaplastic areas.4, 6

Many studies have been conducted to identify the clinical and morphologic features of oligodendrogliomas and to designate the factors affecting survival of patients since 1926.2

More than 90% of oligodendrogliomas are located supratentorially,1, 5 while posterior fossa tumors constitute <10% of all oligodendrogliomas.5, 8, 9, 10, 11 However, oligodendrogliomas arising in the cerebellar peduncle are significantly rare, even <1%.9, 12

Up to now, 6 oligodendroglioma cases localized in the cerebellar peduncle have been presented.12, 13, 14, 15 Solely, one of them originated from the cerebellar peduncle. In this case we aimed to discuss our second case originated from the cerebellar peduncle in company with the literature.

Section snippets

Case Presentation

We report the case of a 43-year-old woman with known hypertension history. Her complaints were headache, perioral numbness, and gait abnormality.

The patient was operated for cerebellopontine angle tumor 2 years ago. Only the biopsy was conducted during this operation. The material was diagnosed as a low-grade glioma, and then the patient was referred to the Radiation Oncology Department.

The patient consulted our clinic because of her unrelieved complaints. Physical examination showed right

Discussion

Oligodendrogliomas are tumors that originate from one of the brain glial cells called an oligodendrocyte.4 Considering that oligodendrogliomas constitute 2%–5% of all primary brain tumors, this type can be counted as the third most common one.5, 11 Oligodendrogliomas constitute 4%–7% of primary intracranial gliomas in adults and 1% of primary central nervous system tumors in children.3, 4, 12

Infratentorial oligodendrogliomas constitute <10% of all oligodendroglial tumors.4, 5, 9, 11, 12

Acknowledgments

This article has been submitted as an e-poster presentation for the 16th World Congress of Neurosurgery that was held in August 2017 in Istanbul, Turkey. We would like to thank Professor Aydin Sav for pathologic examinations.

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Conflict of interest statement: The authors do not have any conflicts of interest to declare.

Deceased in the writing process of the article.

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